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(E/Z)-IT-603
CAS No. : 292168-90-2
Biological Activity：(E/Z)-IT-603 is a mixture of E-IT-603 and Z-IT-603 (IT-603). IT-603 is a c-Rel inhibitor with an IC50 of 3 μM. IT-603 has anti-tumor activity. (E/Z)-IT-603 is a promising modulator of T-cell responses in the context of graft-versus-host disease (GVHD) and malignant diseases.
Research Area：Cancer|Inflammation/Immunology
Targets：NF-κB
Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;NF-κB Signaling Compound Library;Stem Cell Signaling Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Antioxidant Compound Library;Differentiation Inducing Compound Library;Oxygen Sensing Compound Library;Pyroptosis Compound Library;Anti-Breast Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Transcription Factor-Targeted Library;Anti-Liver Cancer Compound Library ;Antidepressant Compound Library;Anti-Prostate Cancer Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:Akt/NF-κB/JNK-IN-1;Icariside F2;IKKγ NBD Inhibitory Peptide TFA;Mangiferin;Antioxidant agent-5;ALPK1-IN-1;Regaloside A;IMD-ferulic;SN52;5-Aminosalicylic Acid-D3 hydrochloride;Ginsenoside Rg1;Echinulin;Licochalcone D;QNZ;BIZ 114;NF-κΒ activator 1;Berbamine;NF-κΒ activator 2;20(S)-Ginsenoside Rg3;Ginsenoside Rd;Morusin;(R)-(-)-Ibuprofen;Ro 106-9920;Armepavine;Laquinimod;S-Allylmercaptocysteine
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