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DYRK1-IN-1
Biological Activity：DYRK1-IN-1 is a highly selective and ligand-efficient DYRK1A inhibitor. DYRK1-IN-1 inhibits DYRK1A phosphorylation activity with an IC50 value of 220 nM. DYRK1-IN-1 can be used for the research of central nervous system penetrant DYRK1A chemical probe.
Research Area：Neurological Disease
Targets：DYRK
Related Screening Libraries:Bioactive Compound Library Plus;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Anti-Obesity Compound Library;
Related Small Molecules:Harmine hydrochloride;T025;ID-8;Dyrk1A-IN-2;GSK-626616;GNF2133 hydrochloride;ARN25068;Haspin-IN-1;LDN-192960 hydrochloride;CLK-IN-T3;GNF4877;DYRKs-IN-2;JH-XIV-68-3;DYRKs-IN-1 hydrochloride;Protein kinase inhibitors 1 hydrochloride;KH-CB20;Dyrk1A/α-synuclein-IN-2;AZ191;Woodtide;CK2/ERK8-IN-1;Dyrk1A-IN-5;ML167;tBID;Dyrk1A-IN-4;Mirk-IN-1;Dyrk1A-IN-1
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