Dovitinib-d8

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Dovitinib-d8

CAS No. : 1246819-84-0

Biological Activity:Dovitinib-D8 (CHIR-258-D8) is the deuterium labeled Dovitinib. Dovitinib (CHIR-258) is a multi-targeted tyrosine kinase inhibitor with IC50s of 1, 2, 8/9, 10/13/8, 27/210 nM for FLT3, c-Kit, FGFR1/FGFR3, VEGFR1/VEGFR2/VEGFR3 and PDGFRα/PDGFRβ, respectively[2].

Research Area:Cancer

Targets:FLT3|VEGFR|c-Kit|FGFR|c-Fms|PDGFR

Related Small Molecules:(Z)-FeCP-oxindole;VEGFR-2-IN-24;BMS-690514;AT9283;PROTAC VEGFR-2 degrader-2;(E/Z)-Zotiraciclib;Henatinib;Crotonoside;PI3K/VEGFR2-IN-1;c-Kit-IN-5-1;Flumatinib mesylate;IHMT-TRK-284;FLT3-IN-13;Ferulic acid-13C3;PDGFRα/FLT3-ITD-IN-2;FLT3/CDK4-IN-1;FGFR-IN-7;PP58;Hydroxytanshinone IIA;Chiauranib;Foretinib;ZM323881 hydrochloride;Zeteletinib;HP1142;FGFR3-IN-1

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