For research use only. We do not sell to patients.

DOV-216,303 Free Base

CAS No. : 66504-40-3

Biological Activity：DOV-216,303 (Free Base) is a potent triple serotonin, norepinephrine, and dopamine reuptake inhibitor, with IC₅₀ values of 14 nM, 20 nM and 78 nM for hSERT, hNET and hDAT, respectively. Has antidepressant-like effects and increases monoamine release in the prefrontal cortex of olfactory bulbectomized (OBX) rats^[2].

Research Area：Neurological Disease

Targets：Dopamine Transporter|Serotonin Transporter

Related Screening Libraries:Bioactive Compound Library Plus;Neuronal Signaling Compound Library;Antidepressant Compound Library;Human Metabolite Library;Coagulation and Anti-coagulation Compound Library;

Related Small Molecules:Diclofensine;Ansofaxine;13-Hydroxyisobakuchiol;Edivoxetine hydrochloride;DSP-1053;Fipexide;Vanoxerine;Azaphen dihydrochloride monohydrate;Wf-516;Nitroxazepine;SPD-473 citrate;Indalpine;Nardoguaianone J;Diclofensine-d3 hydrochloride;Pseudoisocyanine iodide;Roxindole;Cinchonidine;Bisacodyl;AHN 1-055 hydrochloride;BMS-466442;Eplivanserin (mixture)

About Us:

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
Structurally and synthetically diverse biologically active compounds；
roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；

Structurally and synthetically diverse biologically active compounds；

Customized order volume ranging from milligrams to kilograms scale；

We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.

Top Publications Citing Use of MCE Products