For research use only. We do not sell to patients.
DM4-SMe
CAS No. : 796073-68-2
Biological Activity：DM4-SMe is a metabolite of antibody-maytansin conjugates (AMCs) and a tubulin inhibitor, and also a cytotoxic moiety of antibody-drug conjugates (ADCs), which can be linked to antibody through disulfide bond or stable thioether bond. DM4-SMe inhibits KB cells with an IC50 of 0.026 nM[2].
Research Area：Cancer
Targets：Microtubule/Tubulin|ADC Cytotoxin
Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Toxins for Antibody-Drug Conjugate Research Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Covalent Screening Library;Macrocyclic Compound Library;Cytoskeleton Compound Library;Anti-Lung Cancer Compound Library;Protein-protein Interaction Inhibitor Library;
Related Small Molecules:Sandramycin;Tirbanibulin dihydrochloride;Tilavonemab;(R)-Camptothecin-d5;Tau tracer 1;Dolastatin 10;Ceratamine A;INX-SM-56;Batabulin sodium;OXi8007;DC10SMe;Antitumor agent-68;Dictyostatin;Tubulin inhibitor 6;Rebeccamycin;Duocarmycin TM;Oryzalin;Tubulin inhibitor 25;Fmoc-MMAE;Taltobulin;Tubulin inhibitor 16;N-Me-L-Ala-maytansinol;CC-885-CH2-PEG1-NH-CH3;Camptothecin;Epothilone B;TN-16
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
About Us:
- MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
- Structurally and synthetically diverse biologically active compounds；
- roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
- We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
- Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；
- Customized order volume ranging from milligrams to kilograms scale；
Structurally and synthetically diverse biologically active compounds；
We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.
