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Deferoxamine mesylate
CAS No. : 138-14-7
Biological Activity：Deferoxamine mesylate (Deferoxamine B mesylate) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine mesylate upregulates HIF-1α levels with good antioxidant activity. Deferoxamine mesylate also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells. Deferoxamine mesylate can be used in studies of diabetes, neurodegenerative diseases as well as anti-cancer and anti-COVID-19[2][3][4][5].
Research Area：Cancer|Infection|Metabolic Disease|Inflammation/Immunology|Neurological Disease
Targets：Akt|Autophagy|Reactive Oxygen Species|HIF/HIF Prolyl-Hydroxylase|Apoptosis
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Apoptosis Compound Library;Epigenetics Compound Library;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;Metabolism/Protease Compound Library;NF-κB Signaling Compound Library;PI3K/Akt/mTOR Compound Library;Stem Cell Signaling Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;CNS-Penetrant Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Antioxidant Compound Library;Reprogramming Compound Library;Anti-diabetic Compound Library;Oxygen Sensing Compound Library;Ferroptosis Compound Library;Anti-COVID-19 Compound Library;Glycolysis Compound Library;Pyroptosis Compound Library;Cytoskeleton Compound Library;Glutamine Metabolism Compound Library;FDA Approved & Pharmacopeial Drug Library;Neuroprotective Compound Library;Anti-Breast Cancer Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Angiogenesis-Related Compound Library;Mitochondria-Targeted Compound Library;Transcription Factor-Targeted Library;Glucose Metabolism Compound Library;Rare Diseases Drug Library;Children’s Drug Library;Antidepressant Compound Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;
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