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Debio 0617B
CAS No. : 1332329-27-7
Biological Activity：Debio 0617B, a multi-kinase inhibitor, reduces maintenance and self-renewal of primary human AML CD34+ stem/progenitor cells. Debio 0617B has a unique profile targeting key kinases upstream of STAT3/STAT5 signaling such as JAK, SRC, ABL, and class III/V receptor tyrosine kinases (TKs). Debio 0617B has documented efficacy in STAT3-driven solid tumors.
Research Area：Cancer
Targets：JAK|STAT|Bcr-Abl
Related Small Molecules:AZ-3;JAK3/BTK-IN-1;Cirsilineol;Ochromycinone;AT9283;C188-9;Benzene hexabromide;Bafetinib;STAT3-IN-10;(E/Z)-Zotiraciclib;Pivanex;JAK-IN-10;C188;Baricitinib-d3;SNIPER(ABL)-039;Flumatinib mesylate;IHMT-TRK-284;JAK3-IN-6;Niclosamide monohydrate;STAT3-IN-1;STAT3 degrader-1;Coumermycin A1;Deucravacitinib;Momelotinib-3,3,5,5-d4;SNIPER(ABL)-049;PM-81I
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