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Darunavir-d9

CAS No. : 1133378-37-6

Biological Activity：Darunavir-d9 (TMC114-d9) is the deuterium labeled Darunavir. Darunavir (TMC114), an orally active next generation HIV protease inhibitor, has a similar antiviral activity against the mutant and the wild-type viruses. Darunavir (TMC114) is potent against laboratory HIV-1 strains and primary clinical isolates (IC₅₀ = 0.003 μM; IC₉₀ = 0.009 μM) with minimal cytotoxicity^[2].

Research Area：Infection|Inflammation/Immunology

Targets：HIV|HIV Protease

Related Small Molecules:ddCTP trisodium;HIV-1 TAT (48-60);Seletracetam lithium;HIV-IN-2;Triptonine B;FC131;Peritassine A;Flavopiridol;TAT (48-57);FGI-106 tetrahydrochloride;(Z)-9-Propenyladenine;Apabetalone;Decanoyl-RVKR-CMK TFA;ONX-0914 TFA;Apelin-36(rat, mouse);Ulonivirine;Islatravir;HIV-1 inhibitor-19

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