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Danicopan
CAS No. : 1903768-17-1
Biological Activity：Danicopan (ACH-4471), a selective and orally active small-molecule factor D inhibitor, shows high binding affinity to human Factor D with Kd value of 0.54 nM. Danicopan (ACH-4471) inhibits alternative pathway of complement (APC) activity, has potential to block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS).
Research Area：Inflammation/Immunology
Targets：Complement System
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Clinical Compound Library;Drug Repurposing Compound Library;Orally Active Compound Library;Targeted Diversity Library;Rare Diseases Drug Library;
Related Small Molecules:Cemdisiran;Pelecopan;PMX 205;EG00229;Factor B-IN-2;Tesidolumab;Factor B-IN-3;Avacincaptad pegol;Sutimlimab;FD-IN-1;NDT 9513727;Cyclosporin A;AMY-101;Lipoteichoic acid;Iptacopan;Entadamide-A-β-D-glucopyranoside;Compstatin TFA;C5aR-IN-2;BCX 1470;EG01377;TLQP-21;W-54011;Complement C5-IN-1;PMX-53;(Z)-Leukadherin-1
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