For research use only. We do not sell to patients.

Dabigatran (ethyl ester)

CAS No. : 429658-95-7

Biological Activity：Dabigatran ethyl ester is an emerging oral anticoagulant which is a direct inhibitor of thrombin activity.
IC50 value:
Target: thrombin
Dabigatran provides a stable anticoagulation effect without any need to perform periodical laboratory controls. Of note, there is a growing amount of clinical evidence which shows its safety and efficacy. For these reasons, Dabigatran may suppose a revolution in oral anticoagulation. Dabigatran etexilate was rapidly converted to Dabigatran, with peak plasma dabigatran concentrations being attained after approximately 1.5 h; the bioavailability of Dabigatran after p.o. administration of Dabigatran etexilate was 7.2%.

Research Area：Cardiovascular Disease

Targets：Thrombin

Related Screening Libraries:Bioactive Compound Library Plus;

Related Small Molecules:OM-189;Thrombin Inhibitor 2;Razaxaban hydrochloride;Desethyl KBT-3022;Idraparinux sodium;TP508;Inogatran;RWJ-445167;Napsagatran hydrate;BAY 1217224;Thrombin (MW 37kDa);Ximelagatran-d11;Melagatran;(1R,3S)-THCCA-Asn;Sfllrnpndkyepf

About Us:

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
Structurally and synthetically diverse biologically active compounds；
roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；

Structurally and synthetically diverse biologically active compounds；

Customized order volume ranging from milligrams to kilograms scale；

We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.

Top Publications Citing Use of MCE Products