Cyclosporin D

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Cyclosporin D

CAS No. : 63775-96-2

Biological Activity:Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A[2]. Cyclosporin A is a potent immunosuppressant drug, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc)[3].

Research Area:Inflammation/Immunology

Targets:Nuclear Factor of activated T Cells (NFAT)

Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Natural Product Library;Macrocyclic Compound Library;Microbial Metabolite Library;Peptide Library;Cyclic Peptide Library;

Related Small Molecules:(+)-Syringaresinol;NFATc1-IN-1;KRN2;Gomisin E;Heraclenin;11R-VIVIT;CPS-11;KRM-III;NFAT Inhibitor-1;INCA-6;Q134R;KRN5

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