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Cyclic ADP-ribose
CAS No. : 119340-53-3
Biological Activity:Cyclic ADP-ribose (cADPR) is a potent second messenger for calcium mobilization that is synthesized from NAD+ by an ADP-ribosyl cyclase. Cyclic ADP-ribose increases cytosolic calcium mainly by Ryanodine receptor-mediated release from endoplasmic reticulum and also by extracellular influx through the opening of TRPM2 channels[2][3].
Research Area:Infection|Endocrinology|Inflammation/Immunology|Neurological Disease|Cardiovascular Disease
Targets:Calcium Channel|TRP Channel|Endogenous Metabolite
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