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Cot inhibitor-2
CAS No. : 915363-56-3
Biological Activity：Cot inhibitor-2 is a potent, selective and orally active cot (Tpl2/MAP3K8) inhibitor with an IC50 of 1.6 nM. Cot inhibitor-2 inhibts TNF-α production in LPS-stimulated human whole blood with an IC50 of 0.3 μM.
Research Area：Cancer
Targets：MAP3K
Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;MAPK Compound Library;Anti-Cancer Compound Library;Oxygen Sensing Compound Library;Orally Active Compound Library;Anti-Obesity Compound Library;Targeted Diversity Library;Cancer Stem Cells Compound Library;
Related Small Molecules:TAK1-IN-2;ASK1-IN-3;Takinib;PF-05381941;SM1-71;NQDI-1;GS-444217;TC ASK 10;DLK-IN-1;7,3′,4′-Trihydroxyisoflavone;TAK1-IN-4;Selonsertib;Cot inhibitor-1;TAK1/MAP4K2 inhibitor 1;5Z-7-Oxozeaenol;Tpl2 Kinase Inhibitor 1;SW083688;ASK1-IN-2;TAO Kinase inhibitor 1;GNE-8505;GNE-3511;NG25;TAK1-IN-3
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