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Chelerythrine chloride
CAS No. : 3895-92-9
Biological Activity：Chelerythrine chloride is a potent, cell-permeable inhibitor of protein kinase C, with an IC50 of 660 nM. Chelerythrine chloride inhibits the Bcl-XL-Bak BH3 peptide binding with IC50 of 1.5 μM and displaces Bax from Bcl-XL. Chelerythrine chloride induces apoptosis and autophagy.
Research Area：Cancer|Metabolic Disease|Inflammation/Immunology
Targets：Autophagy|PKC|Bcl-2 Family|Apoptosis
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