For research use only. We do not sell to patients.
ChE/Aβ1-42-IN-1
Biological Activity：ChE/Aβ1-42-IN-1 (compound 28) is a potent ChE and Aβ1-42 aggregation inhibitor with IC50s of 0.062, 0.767 and 1.227 µM for AChE, BuChE and Aβ1-42 aggregation, respectively. ChE/β1-42-IN-1 shows excellent BBB penetration. ChE/Aβ1-42-IN-1 is a potent multi-targeted anti-Alzheimer’s agent.
Research Area：Neurological Disease
Targets：Amyloid-β|Cholinesterase (ChE)
Related Small Molecules:β-Amyloid (13-27);Saikosaponin C;β-Amyloid (1-42), (rat/mouse) (TFA);Piperilate;β-Amyloid (12-28) (TFA);BuChE-IN-5;Ginsenoside Rg1;MDR-1339;AChE/BChE-IN-10;Timosaponin AIII;Trimyristin;AChE-IN-10;Isoimperatorin;Pseudocoptisine chloride;Itopride-d6 hydrochloride;β-Amyloid (11-22);Sinapine thiocyanate;sEH/AChE-IN-1;AChE-IN-11;20(S)-Ginsenoside Rg3;β-Amyloid (31-35);Heliosupine;(-)-Cyclopenin;Aβ-IN-1;Leptomerine
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Structurally and synthetically diverse biologically active compounds；
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