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Cerivastatin sodium

CAS No. : 143201-11-0

Biological Activity：Cerivastatin sodium is a synthetic lipid-lowering agent and a highly potent, well-tolerated and orally active HMG-CoA reductase inhibitor, with a Ki of 1.3 nM/L. Cerivastatin sodium reduces low-density lipoprotein cholesterol levels. Cerivastatin sodium also inhibits proliferation and invasiveness of MDA-MB-231 cells, mainly by RhoA inhibition, and has anti-cancer effect^[2].

Research Area：Cancer|Cardiovascular Disease

Targets：Ferroptosis|HMG-CoA Reductase (HMGCR)

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Apoptosis Compound Library;Metabolism/Protease Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Drug Repurposing Compound Library;Anti-Cardiovascular Disease Compound Library;Ferroptosis Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Cancer Metabolism Compound Library;Lipid Metabolism Compound Library ;FDA-Approved Anticancer Drug Library;

Related Small Molecules:CIL56;DB0614;Ciclopirox-d11;Ciclopirox olamine;Curcumin;β-Amyrin acetate;SR12813;(-)-Epicatechin;Eugenol-d3;Artemisinin-d3;MMRi62;UAMC-3203;L-Glutamic acid-15N,d5;Chalcones A-N-5;Pifithrin-β hydrobromide;PD146176;Roxadustat;Matrine;Liproxstatin-1;Hemin

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