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CDDO-dhTFEA
CAS No. : 1191265-33-4
Biological Activity：CDDO-dhTFEA (RTA dh404) is a synthetic oleanane triterpenoid compound which potently activates Nrf2 and inhibits the pro-inflammatory transcription factor NF-κB. CDDO-dhTFEA restores hypertension (MAP), increases Nrf2 and expression of its target genes, attenuates activation of NF-κB and transforming growth factor-β pathways, and reduces glomerulosclerosis, interstitial fibrosis and inflammation in the chronic kidney disease (CKD) rats[2].
Research Area：Inflammation/Immunology
Targets：Keap1-Nrf2|NF-κB
Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;NF-κB Signaling Compound Library;Stem Cell Signaling Compound Library;Anti-Aging Compound Library;Covalent Screening Library;Antioxidant Compound Library;Differentiation Inducing Compound Library;Oxygen Sensing Compound Library;Ferroptosis Compound Library;Pyroptosis Compound Library;Anti-Breast Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Transcription Factor-Targeted Library;Anti-Liver Cancer Compound Library ;Antidepressant Compound Library;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:Akt/NF-κB/JNK-IN-1;Icariside F2;IKKγ NBD Inhibitory Peptide TFA;Mangiferin;Antioxidant agent-5;Curcumin;ALPK1-IN-1;Regaloside A;IMD-ferulic;SN52;5-Aminosalicylic Acid-D3 hydrochloride;Ginsenoside Rg1;Echinulin;Antroquinonol;Licochalcone D;QNZ;BIZ 114;NF-κΒ activator 1;Berbamine;NF-κΒ activator 2;20(S)-Ginsenoside Rg3;Resveratrol;Ginsenoside Rd;NXPZ-2;Morusin;(R)-(-)-Ibuprofen;Ro 106-9920
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