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Calmodulin antagonist-1
CAS No. : 78957-84-3
Biological Activity:Calmodulin antagonist-1 (W-7) is a calmodulin (CaM) antagonist. Calmodulin antagonist-1 inhibits calmodulin-activated Ca2+-phosphodiesterase (PDE) (IC50=28 μM). Calmodulin antagonist-1 also inhibits trypsin-treated Ca2+-PDE (IC50=375 μM) in a competitive fashion with respect to cyclic GMP and the Ki value is 300 μM.
Research Area:Cardiovascular Disease
Targets:Calmodulin
Related Small Molecules:Psoralenoside;CALP1;CV-159;W-7 hydrochloride;Calmodulin Binding Peptide 1;Acremonidin A;CALP2;Neurogranin (48-76), mouse;Stains-All;Metofenazate;Acremoxanthone C
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