AZT triphosphate TEA

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AZT triphosphate TEA

Biological Activity:AZT triphosphate TEA (3′-Azido-3′-deoxythymidine-5′-triphosphate TEA) is a active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate TEA exhibits antiretroviral activity and inhibits replication of HIV. AZT triphosphate TEA also inhibits the DNA polymerase of HBV. AZT triphosphate TEA activates the mitochondria-mediated apoptosis pathway[2][3].

Research Area:Infection

Targets:DNA/RNA Synthesis|Reactive Oxygen Species|HIV|HBV|Apoptosis

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