Atraric acid

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Atraric acid

CAS No. : 4707-47-5

Biological Activity:Atraric acid (Methyl atrarate) is a specific androgen receptor (AR) antagonist with anti-inflammatory and anticancer effects. Atraric acid represses the expression of the endogenous prostate specific antigen gene in both LNCaP and C4-2 cells. Atraric acid can also inhibit the synthesis of NO and cytokine, and suppress the MAPK-NFκB signaling pathway. Atraric acid can be used to research prostate diseases and inflammatory diseases[2].

Research Area:Cancer|Inflammation/Immunology

Targets:Androgen Receptor|NF-κB|p38 MAPK|NO Synthase

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