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Apogossypolone
CAS No. : 886578-07-0
Biological Activity:Apogossypolone (ApoG2) is an orally active Bcl-2 family proteins inhibitor with Ki values of 35, 25 and 660 nM for Bcl-2, Mcl-1 and Bcl-XL, respectively. Apogossypolone shows antitumor activities, induces cell apoptosis and autophagy[2]. Apogossypolone also has antifungal activity[3].
Research Area:Cancer|Infection
Targets:Fungal|Autophagy|Bcl-2 Family|ROS Kinase|Apoptosis
Related Small Molecules:Antifungal agent 20;Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;Debneyol;BJE6-106;Dinaciclib;Haloprogin;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;BI-3812;Xevinapant;Ciclopirox-d11;Mangiferin;Cambinol;Antioxidant agent-5
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