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Agrimol B
CAS No. : 55576-66-4
Biological Activity:Agrimol B, a polyphenol, is an orally active and potent SIRT1 activator. Agrimol B shows anti-adipogenic and anticancer activity. Agrimol B shows antibacterial activity against plant pathogens. Agrimol B dramatically inhibits 3T3-L1 adipocyte differentiation by reducing PPARγ, C/EBPα, FAS, UCP-1, and apoE expression. The action of Agrimol B on the cancer cells is likely derived from its effect on c-MYC, SKP2 and p27[2][3].
Research Area:Cancer|Infection|Metabolic Disease
Targets:Fatty Acid Synthase (FASN)|PPAR|Bacterial|Sirtuin|c-Myc
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