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Abemaciclib metabolite M18-d8
Biological Activity：Abemaciclib metabolite M18-d8 (LSN3106729-d8) is the deuterium labeled Abemaciclib metabolite M18. Abemaciclib metabolite M18 (LSN3106729), the metabolite of Abemaciclib (HY-16297A), is a CDK inhibitor with antitumor activity. Abemaciclib metabolite M18 and a CRBN ligand have been used to design PROTAC CDK4/6 degrader[2].
Research Area：Cancer
Targets：Ligands for Target Protein for PROTAC|CDK
Related Small Molecules:DB0614;Dinaciclib;SNS-032;CC-671;(E/Z)-Zotiraciclib;CDK1-IN-4;CCT-251921;BS-181;Samuraciclib hydrochloride hydrate;T025;Flavopiridol;CDK8-IN-3;CDK9-IN-12;FLT3/CDK4-IN-1;GFB-12811;GSK 3 Inhibitor IX;Eciruciclib;BI-4464;CDK-IN-6;PROTAC BRD4 ligand-2;Lerociclib dihydrochloride;CDK4/6-IN-13;PROTAC BRD9-binding moiety 1 hydrochloride;ON-013100;PROTAC IRAK4 ligand-1;Apcin-A;(2S,3R)-Voruciclib hydrochloride;Cucurbitacin E;THZ1
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