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6-Diazo-5-oxo-L-nor-Leucine
CAS No. : 157-03-9
Biological Activity：6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity[2][3].
Research Area：Cancer|Infection
Targets：Influenza Virus|Glutaminase|Bacterial|Antibiotic
Related Screening Libraries:Bioactive Compound Library Plus;Anti-Infection Compound Library;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Antiviral Compound Library;Antibacterial Compound Library;Glutamine Metabolism Compound Library;Antibiotics Library;Anti-Pancreatic Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Mitochondria-Targeted Compound Library;Cuproptosis Compound Library;
Related Small Molecules:Sandramycin;LLO (91-99);Gepotidacin;Oritavancin;Monascorubrin;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin;Antibacterial agent 99;Vidarabine monohydrate;Nafcillin;Antitubercular agent-28;Ochromycinone;Staurosporine;Nucleocidin;(±)-Leucine-13C-1;Ciclopirox-d11;Ciclopirox olamine;Clotrimazole-d5;Curcumin;SQ109
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