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4-Hydroperoxy Cyclophosphamide-d4
CAS No. : 1246816-71-6
Biological Activity：4-Hydroperoxy Cyclophosphamide-d4 is the deuterium labeled 4-Hydroperoxy cyclophosphamide. 4-Hydroperoxy cyclophosphamide is the active metabolite form of the prodrug Cyclophosphamide. 4-Hydroperoxy cyclophosphamide crosslinks DNA and induces T cell apoptosis independent of death receptor activation, but activates mitochondrial death pathways through production of reactive oxygen species (ROS). 4-Hydroperoxy cyclophosphamide has the potential for lymphomas and autoimmune disorders[2].
Research Area：Inflammation/Immunology
Targets：Drug Metabolite|DNA Alkylator/Crosslinker|Reactive Oxygen Species|Apoptosis
Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Physalin A;Nicotinamide N-oxide;Bomedemstat ditosylate;Chitoheptaose heptahydrochloride;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;N-Acetyl-D-cysteine;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;CYPMPO;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5
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