4′-Hydroxywogonin

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4′-Hydroxywogonin

CAS No. : 57096-02-3

Biological Activity:4′-Hydroxywogonin (8-Methoxyapigenin), a flavonoid, could be isolated from a variety of plants including Scutellaria barbata and Verbena littoralis. 4′-Hydroxywogonin has anti-inflammatory activity via TAK1/IKK/NF-κB, MAPKs and PI3/AKT signaling pathways. 4′-Hydroxywogonin inhibits angiogenesis by disrupting PI3K/AKT signaling. 4′-Hydroxywogonin inhibits cell proliferation and induces apoptosis[2][3].

Research Area:Cancer|Inflammation/Immunology|Cardiovascular Disease

Targets:Akt|TNF Receptor|Interleukin Related|NF-κB|p38 MAPK|Reactive Oxygen Species|Bcl-2 Family|IKK|Caspase|Apoptosis|PI3K

Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Physalin A;Bomedemstat ditosylate;Akt/NF-κB/JNK-IN-1;Chitoheptaose heptahydrochloride;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;Umbralisib hydrochloride;AX-024;Icariside F2;N-Acetyl-D-cysteine;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;IKKγ NBD Inhibitory Peptide TFA;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;BI-3812;CYPMPO

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