For research use only. We do not sell to patients.
(3S,5R)-Rosuvastatin
CAS No. : 1242184-42-4
Biological Activity：(3S,5R)-Rosuvastatin is the (3S,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM. Rosuvastatin potently blocks human ether-a-go-go related gene (hERG) current with an IC50 of 195 nM[2]. Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin is very effective in lowering low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels[3].
Research Area：Metabolic Disease|Cardiovascular Disease
Targets：Autophagy|Potassium Channel|HMG-CoA Reductase (HMGCR)
Related Small Molecules:Kv3 modulator 2;Brompheniramine-d6 maleate;Pinacidil;AMP-PNP tetralithium;β-Amyrin acetate;IK1 inhibitor PA-6;SR12813;VU590;Domiphen bromide;Mesoridazine benzenesulfonate;Tetrandrine;20(S)-Ginsenoside Rg3;(S)-(+)-Modafinic acid-d5;Ketanserin;PE 22-28;Ifenprodil tartrate;Brompheniramine maleate;L-Palmitoylcarnitine-d3 hydrochloride;Phe-Met-Arg-Phe amide trifluoroacetate;Mitiglinide;Flupirtine-d4 hydrochloride
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
About Us:
- MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
- Structurally and synthetically diverse biologically active compounds；
- roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
- We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
- Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；
- Customized order volume ranging from milligrams to kilograms scale；
Structurally and synthetically diverse biologically active compounds；
We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.
