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11-Ketodihydrotestosterone

CAS No. : 32694-37-4

Biological Activity：11-Ketodihydrotestosterone (11-KDHT; 5α-Dihydro-11-keto testosterone) is an endogenous steroid and a metabolite of 11β-Hydroxyandrostenedione. 11-Ketodihydrotestosterone is an active androgen and is also a potent androgen receptor (AR) agonist with a K_i of 20.4 nM and an EC₅₀ of 1.35 nM for human AR. 11-Ketodihydrotestosterone drives gene regulation, protein expression and cell growth in androgen-dependent prostate cancer cells^[2].

Research Area：Endocrinology

Targets：Androgen Receptor

Related Screening Libraries:Bioactive Compound Library Plus;Lipid Compound Library;Endocrinology Compound Library;Transcription Factor-Targeted Library;Anti-Prostate Cancer Compound Library;Nuclear Receptor Compound Library;

Related Small Molecules:VPC-14449;AC-262536;GTx-007;Linuron-d6;MI-136;VPC-13789;RD162;ARD-2585;PF-998425;GSK-2881078;PROTAC AR Degrader-4;RU 58841;Triptophenolide;ARD-61;Dehydroisoandrosterone 3-acetate;Topilutamide;CSRM617 hydrochloride;ARD-2128;A4B17;MK-0773;LH-RH II (chicken)

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