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α-Thujone
CAS No. : 546-80-5
Biological Activity：α-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC50 for α-Thujone is 21 μM in suppressing the GABA-induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and easily penetrates the blood-brain barrier[2][3].
Research Area：Cancer|Infection|Neurological Disease
Targets：Parasite|Autophagy|Reactive Oxygen Species|GABA Receptor|Apoptosis
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