Zatebradine hydrochloride

For research use only. We do not sell to patients.

Zatebradine hydrochloride

CAS No. : 91940-87-3

Biological Activity:Zatebradine (UL-FS-49 (free base)) is a potent inhibitor of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels with an IC50 values 1.96 µM. Zatebradine blocks the slow inward current through human HCN1, HCN2, HCN3 and HCN4 channels, with IC50 values of 1.83 µM, 2.21 µM, 1.90 µM and 1.88 µM, respectively.

Research Area:Cardiovascular Disease

Targets:HCN Channel

Related Screening Libraries:Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Anti-Cardiovascular Disease Compound Library;Targeted Diversity Library;Human Metabolite Library;

Related Small Molecules:Cilobradine hydrochloride;Ivabradine hydrochloride;ZD7288;ZD 7288-d3

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