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Voxtalisib

CAS No. : 934493-76-2

Biological Activity：Voxtalisib (XL765) is a potent PI3K inhibitor, which has a similar activity toward class I PI3K (IC₅₀s=39, 113, 9 and 43 nM for p110α, p110β, p110γ and p110δ, respectively), also inhibits DNA-PK (IC₅₀=150 nM) and mTOR (IC₅₀=157 nM). Voxtalisib (XL765) inhibits mTORC1 and mTORC2 with IC₅₀s of 160 and 910 nM, respectively.

Research Area：Cancer

Targets：mTOR|PI3K

Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Kinase Inhibitor Library;PI3K/Akt/mTOR Compound Library;Stem Cell Signaling Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Antioxidant Compound Library;Differentiation Inducing Compound Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Anti-COVID-19 Compound Library;Glycolysis Compound Library;Cytoskeleton Compound Library;Glutamine Metabolism Compound Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Lipid Metabolism Compound Library ;Glucose Metabolism Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Human Metabolite Library;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;

Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Umbralisib hydrochloride;Topoisomerase I/II inhibitor 3;Cyclovirobuxine D;Rigosertib sodium;Tenalisib R Enantiomer;PI3kδ inhibitor 1;WYE-354;PI3K/VEGFR2-IN-1;L-Leucine-1-13C,15N;1,3-Dicaffeoylquinic acid;PI3Kδ-IN-1;PI-103-d8;Palomid 529;PI3Kα-IN-8;PI-103 Hydrochloride;RMC-5552;OXA-01;L-Leucine-15N;IC-87114;PI3K/mTOR Inhibitor-6;PI3K-IN-10;SF2523;PI3K-IN-29;PI3K/mTOR Inhibitor-1;PI3K-IN-26;GSK-F1;Serabelisib

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