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Varespladib sodium

CAS No. : 172733-42-5

Biological Activity：Varespladib sodium (LY315920 sodium) is a potent and selective group IIA, secretory phospholipase A₂ (sPLA₂) inhibitor with an IC₅₀ of 9 nM. Varespladib sodium exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC₅₀s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively.

Research Area：Inflammation/Immunology

Targets：Phospholipase

Related Small Molecules:GK563;DPTIP;Cambinol;Neomycin sulfate;ONO-RS-082;ARN19874;LEI-401;ST271;Melittin TFA;(S)-Bromoenol lactone;GK187;D-Erythro-dihydrosphingosine-d7;FKGK11;PACOCF3;DL-erythro-Dihydrosphingosine;1-Naphthaleneacetic acid potassium salt;C12 NBD Sphingomyelin;ML-298;sPLA2-X Inhibitor 31;Tanshinone I;(R)-Bromoenol lactone;Ecopladib;LY 178002;CAY10502;(2E)-OBAA;ML348

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