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Thioridazine hydrochloride
CAS No. : 130-61-0
Biological Activity：Thioridazine hydrochloride, an orally active antagonist of the dopamine receptor D2 family proteins, exhibits potent anti-psychotic and anti-anxiety activities. Thioridazine hydrochloride is also a potent inhibitor of PI3K-Akt-mTOR signaling pathways with anti-angiogenic effect. Thioridazine hydrochloride shows antiproliferative and apoptosis induction effects in various types of cancer cells, with specificity on targeting cancer stem cells (CSCs)[2][3][4].
Research Area：Cancer|Infection|Neurological Disease
Targets：Dopamine Receptor|5-HT Receptor|Autophagy|Bacterial|Apoptosis
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Apoptosis Compound Library;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;CNS-Penetrant Compound Library;Autophagy Compound Library;Drug Repurposing Compound Library;Antibacterial Compound Library;Anti-COVID-19 Compound Library;NMPA-Approved Drug Library;Orally Active Compound Library;Neurotransmitter Receptor Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Alzheimer’s Disease Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;5-HT Receptor Compound Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Anti-Aging Natural Product Library;Coagulation and Anti-coagulation Compound Library;
Related Small Molecules:Physalin A;Bomedemstat ditosylate;F 13714;Sandramycin;LLO (91-99);Gepotidacin;Enpp/Carbonic anhydrase-IN-1;Alizapride hydrochloride;GK563;Calpeptin;Thioproperazine;Oritavancin;Lobetyolin;Azlocillin sodium salt;Mosapride-d5;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin
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