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TBK1/IKKε-IN-5
CAS No. : 1893397-65-3
Biological Activity：TBK1/IKKε-IN-5 (compound 1) is an orally active TBK1 and IKKε dual inhibitor, with IC50 values of 1 and 5.6 nM, respectively. TBK1/IKKε-IN-5 enhances the blockade response to PD-1 and induces immune memory in rats when combines with anti-PD-L1. TBK1/IKKε-IN-5 can be used in cancer research, especially in tumour immunity.
Research Area：Cancer
Targets：IKK
Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;NF-κB Signaling Compound Library;Stem Cell Signaling Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Covalent Screening Library;Differentiation Inducing Compound Library;Orally Active Compound Library;Anti-Blood Cancer Compound Library;Anti-Liver Cancer Compound Library ;Anti-Prostate Cancer Compound Library;
Related Small Molecules:PS-1145;NF-κB-IN-1;Resveratrol;IKK-IN-3;Anti-inflammatory agent 6;PF-184;BOT-64;Siegesbeckialide I;LY2409881;Tizoxanide;Bay 65-1942 (R form);IKK 16;AZD3264;Chicanine;Resveratrol-d4;IMD-0560;GSK319347A;IKK-IN-1;Ertiprotafib;ACHP Hydrochloride;IKK2-IN-3;TPCA-1;DMX-129;Resveratrol analog 2
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