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TAK-715
CAS No. : 303162-79-0
Biological Activity：TAK-715 is an orally active and potent p38 MAPK inhibitor with IC50s of 7.1 nM, 200 nM for p38α and p38β, respectively. TAK-715 inhibits casein kinase I (CK1δ/ε) to regulate activation of Wnt/β-catenin signaling. TAK-715 shows good significant efficacy in a rat arthritis model[2].
Research Area：Inflammation/Immunology
Targets：p38 MAPK|Casein Kinase
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;MAPK Compound Library;Stem Cell Signaling Compound Library;Wnt/Hedgehog/Notch Compound Library;Clinical Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Anti-COVID-19 Compound Library;Pyroptosis Compound Library;Orally Active Compound Library;Anti-Lung Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Neurodegenerative Disease-related Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Rare Diseases Drug Library;Antidepressant Compound Library;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:Umbralisib hydrochloride;SB-747651A dihydrochloride;Dehydrocorydaline;SKF-86002 dihydrochloride;4,5,6,7-Tetrabromo-1H-benzimidazole;Pexmetinib;SB 242235;TA-01;Ellagic acid;Anti-inflammatory agent 7;CK2 inhibitor 3;MW-150;VX-702;TMCB;R1487 Hydrochloride;MBP MAPK Substrate;Isoliquiritin apioside;Sesamolin;CK2 inhibitor 2;MAPK13-IN-1;PF-05381941;Longdaysin;Semapimod tetrahydrochloride;D4476;SD-169;Skatole;BMS-582949 hydrochloride;Gypenoside L
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