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Tafluprost acid-d4

Biological Activity：Tafluprost acid-d4 is the deuterium labeled Tafluprost acid. Tafluprost acid (AFP-172), an active metabolic form of Tafluprost, is a selective prostanoid FP receptor agonist. Tafluprost acid shows a high affinity for human prostanoid FP receptor with K_i and EC₅₀ values of 0.4 nM and 0.53 nM, respectively. Tafluprost acid has 126 times weaker binding affinity for prostanoid EP3 receptor (IC₅₀=67 nM) than for the prostanoid FP receptor. Tafluprost acid can be used in the research of glaucoma^[2]^[3].

Research Area：Endocrinology|Neurological Disease|Cardiovascular Disease

Targets：Drug Metabolite|Prostaglandin Receptor

Related Small Molecules:Nicotinamide N-oxide;4-Hydroxyphenylbutazone;Omidenepag isopropyl;Ampyrone;Resveratrol-3-O-sulfate sodium;DG-041;Sonidegib metabolite M48;Isonicotinic acid;8-Isoprostaglandin E2;BAY-6672;trans-Isoferulic acid;Cycloguanil hydrochloride;GSK-269984A;KMN-80;Hydroxytanshinone IIA;SC 51089;Endoxifen;p-Hydroxycinnamic acid

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