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SP-100030
CAS No. : 154563-54-9
Biological Activity：SP-100030 is a potent NF-κB and activator protein-1 (AP-1) double inhibitor (IC50s=50 and 50 nM, respectively). SP-100030 inhibits IL-2, IL-8, and TNF-alpha production in Jurkat and other T cell lines. SP-100030 decreases murine collagen-induced arthritis (CIA)[2].
Research Area：Inflammation/Immunology
Targets：NF-κB
Related Screening Libraries:Covalent Screening Library Plus; Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;NF-κB Signaling Compound Library;Stem Cell Signaling Compound Library;Anti-Aging Compound Library;Covalent Screening Library;Antioxidant Compound Library;Differentiation Inducing Compound Library;Oxygen Sensing Compound Library;Pyroptosis Compound Library;Anti-Breast Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Transcription Factor-Targeted Library;Anti-Liver Cancer Compound Library ;Antidepressant Compound Library;Anti-Prostate Cancer Compound Library;Chemokine Compound Library;Cancer Stem Cells Compound Library;Coagulation and Anti-coagulation Compound Library;
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