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SD-1008
CAS No. : 960201-81-4
Biological Activity：SD-1008 is a potent JAK inhibitor. SD-1008 inhibits tyrosyl phosphorylation of STAT3, JAK2 and Src. SD-1008 also reduces STAT3-dependent luciferase activity. SD-1008 enhances apoptosis induced by Paclitaxel in ovarian cancer cells via directly blocking the JAK-STAT3 signaling pathway.
Research Area：Cancer
Targets：JAK|STAT|Apoptosis
Related Small Molecules:Physalin A;Bomedemstat ditosylate;AZ-3;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;JAK3/BTK-IN-1;BJE6-106;Dinaciclib;Cirsilineol;Ecteinascidin 770;MDM2-p53-IN-15;Ochromycinone;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Benzene hexabromide;Mangiferin;Cambinol;Antioxidant agent-5
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