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(S)-BI 665915

CAS No. : 1360550-05-5

Biological Activity：(S)-BI 665915 is an orally active oxadiazole-containing 5-lipoxygenase-activating protein (FLAP) inhibitor with an IC₅₀ of 1.7 nM for FLAP binding. (S)-BI 665915 inhibits FLAP functional in human whole blood with an IC₅₀ of 45 nM. (S)-BI 665915 demonstrates an excellent cross-species drug metabolism and pharmacokinetics (DMPK) profile and a dose-dependent inhibition of LTB₄ production.

Research Area：Inflammation/Immunology

Targets：FLAP

Related Small Molecules:MK-886;AM103;Fiboflapon;AM679;Veliflapon;Quiflapon sodium;Diflapolin;Atuliflapon

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides

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