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RO5256390
CAS No. : 1043495-96-0
Biological Activity:RO5256390 is an agonist of trace amine-associated receptor 1 (TAAR1), a highly conserved G-protein-coupled receptor (GPCR) bound by endogenous trace amines.
RO5256390 can be used to reduce multiple behavioral effects of drugs of abuse through their actions on the mesocorticolimbic system.
RO5256390 is a modulator of monoaminergic neurotransmission, blocks psychostimulant-induced hyperactivity and produces a brain activation pattern reminiscent of the antipsychotic drug olanzapine, suggesting antipsychotic-like properties[2].
Research Area:Neurological Disease
Targets:Trace Amine-associated Receptor (TAAR)
Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Lipid Metabolism Compound Library ;
Related Small Molecules:Ro 5212773-d5;RO5166017;RO5263397;Ro 5212773;Ralmitaront
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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