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PR-104
CAS No. : 851627-62-8
Biological Activity:PR-104 is a selective hypoxia-activated DNA cross-linking agent and can be used for the research of multiple tumor xenograft models. PR-104, as a nitrogen mustard pre-prodrug, is converted efficiently to the more lipophilic dinitrobenzamide mustards alcohol PR-104A.
Research Area:Cancer
Targets:DNA Alkylator/Crosslinker
Related Screening Libraries:Covalent Screening Library Plus;Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Covalent Screening Library;Anti-Lung Cancer Compound Library;
Related Small Molecules:Anticancer agent 11;Tesirine;DC10SMe;Duocarmycin TM;Prednimustine;Sibiromycin;Lurbinectedin;Phenylacetic acid mustard;PR-104A;Duocarmycin SA;Duocarmycin DM free base;Imifoplatin;NCI172112;Satraplatin;Trioxsalen;Duocarmycin MA;Miriplatin (hydrate)
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