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PPADS tetrasodium

CAS No. : 192575-19-2

Biological Activity：PPADS tetrasodiuma is a non-selective P2X receptor antagonist. PPADS tetrasodiuma blocks recombinant P2X1, -2, -3, -5 with IC₅₀s ranging from 1 to 2.6 μM. PPADS tetrasodiuma blocks native P2Y2-like (IC₅₀~0.9 mM) and recombinant P2Y4 (IC₅₀~15 mM) receptors. PPADS tetrasodiuma is an inhibitor of the reverse mode of the Na/Ca²⁺ exchanger in guinea pig airway smooth muscle^[2].

Research Area：Neurological Disease

Targets：P2X Receptor|Na+/Ca2+ Exchanger

Related Screening Libraries:Bioactive Compound Library Plus;

Related Small Molecules:Gefapixant citrate;SN 6;JNJ-47965567;AF-353;Oxatomide;AZ10606120 dihydrochloride;Taspine;A-317491;NF449 octasodium;A-804598;SM-6586;Benzamil hydrochloride;P2X receptor-1;Aurintricarboxylic acid;Minodronic acid;NF023 hexasodium;A 438079 hydrochloride;KN-62;Opiranserin;GW791343 dihydrochloride;5-BDBD;NF279;Terfenadine;Lu AF27139;JNJ-55308942;PPNDS tetrasodium;KB-R7943 mesylate

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