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PI3K/HDAC-IN-2
CAS No. : 2361418-65-5
Biological Activity：PI3K/HDAC-IN-2 is a potent dual PI3K/HDAC inhibitor with IC50s of 226 nM, 279 nM, 467 nM, 29 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ, respectively, and IC50s of 1.3 nM, 3.4 nM, 972 nM, 17 nM, 12 nM for HDAC1, HDAC2, HDC4, HDAC6, HDAC8, respectively. PI3K/HDAC-IN-2 exhibits PI3Kδ and class I and IIb HDAC selectivity. PI3K/HDAC-IN-2 has remarkable anticancer effects.
Research Area：Cancer
Targets：HDAC|PI3K
Related Small Molecules:Umbralisib hydrochloride;Topoisomerase I/II inhibitor 3;Rigosertib sodium;Tenalisib R Enantiomer;Pivanex;PI3kδ inhibitor 1;Crotonoside;MPT0B390;PI3K/VEGFR2-IN-1;RSC133;HDAC1/6-IN-1;HDAC/HSP90-IN-4;JPS014;1,3-Dicaffeoylquinic acid;PI3Kδ-IN-1;PI-103-d8;PI3Kα-IN-8;HDAC-IN-4;PI-103 Hydrochloride;HDAC-IN-27;1-Alaninechlamydocin;IC-87114;SKLB-23bb;Tacedinaline;PI3K/mTOR Inhibitor-6;PI3K-IN-10;SF2523;PI3K-IN-29
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