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PFK-015

CAS No. : 4382-63-2

Biological Activity：PFK-015, a derivative of 3PO, is a specific PFKFB3 inhibitor. PFK-015 inhibits recombinant PFKFB3 with an IC₅₀ value of 110 nM and inhibits PFKFB3 activity in cancer cells with an IC₅₀ value of 20 nM. PFK-015 can be used for the research of multiple cancers such as lung cancer, stomach cancer, colon cancer and esophageal squamous cell carcinoma (ESCC)^[2].

Research Area：Cancer|Metabolic Disease|Inflammation/Immunology

Targets：Autophagy

Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Anti-Cancer Compound Library;Autophagy Compound Library;Anti-Lung Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Colorectal Cancer Compound Library ;

Related Small Molecules:Physalin A;Stauprimide;Pregnenolone monosulfate sodium;Notoginsenoside Fc;AGN 193109-d7;AT9283;Ciclopirox-d11;BIX-01294;Wogonoside;Cyclovirobuxine D;Clotrimazole-d5;Curcumin;Loperamide-d6 N-Oxide;Physalin B;Colistin sulfate;Salvianolic acid B;10074-G5;Dehydrocorydaline;Glucosamine-13C hydrochloride

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