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Pentamidine-d4 dihydrochloride

CAS No. : 1276197-32-0

Biological Activity：Pentamidine-d4 (MP-601205-d4) dihydrochloride is the deuterium labeled Pentamidine dihydrochloride. Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine dihydrochloride inhibits parasite Leishmania infantum with an IC₅₀ of 2.5 μM. Pentamidine dihydrochloride is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine dihydrochloride has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities^[2]^[3]^[4].

Research Area：Cancer|Infection

Targets：Parasite|Fungal|Bacterial|Antibiotic|Phosphatase

Related Small Molecules:Antifungal agent 20;(+)-Isopulegol;Sandramycin;LLO (91-99);Gepotidacin;Oritavancin;Monascorubrin;SR9186;Antileishmanial agent-2;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Debneyol;Leucomycin;Isouvaretin;Haloprogin;GNF362;Antibacterial agent 99;Vidarabine monohydrate;Nafcillin;Antitubercular agent-28

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