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Pamoic acid disodium

CAS No. : 6640-22-8

Biological Activity：Pamoic acid disodium is a potent GPR35 agonist with an EC₅₀ value of 79 nM. Pamoic acid disodium induces GPR35 internalization and activates ERK1/2 with EC₅₀ values of 22 nM and 65 nM, respectively. Pamoic acid disodium potently recruits β-arrestin2 to GPR35 and has an antinociceptive effect.

Research Area：Neurological Disease

Targets：GPR35|ERK

Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;MAPK Compound Library;Stem Cell Signaling Compound Library;Anti-Aging Compound Library;Oxygen Sensing Compound Library;Glutamine Metabolism Compound Library;Neuroprotective Compound Library;Angiogenesis-Related Compound Library;Antidepressant Compound Library;Osteogenesis Compound Library;

Related Small Molecules:Corynoxeine;Temuterkib;CKLF1-C27;LM22B-10;ERK5-IN-4;Pachymic acid;MAP855;CID1231538;6-OAU;VX-11e;Pluripotin;2,5-Dihydroxyacetophenone;Astragaloside IV;ERK1/2 inhibitor 1;Longdaysin;[Tyr8] Bradykinin;Gypenoside L;ERK-IN-2;Omtriptolide;Chemerin-9 (149-157);MAPK-IN-1;SHR2415;Anti-inflammatory agent 31;PACAP-38 (31-38), human, mouse, rat TFA;AKT-IN-11;N-Salicyloyltryptamine

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