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Orelabrutinib
CAS No. : 1655504-04-3
Biological Activity：Orelabrutinib (ICP-022) is a potent, orally active, and irreversible Bruton’s tyrosine kinase (BTK) inhibitor with potential antineoplastic activity. Orelabrutinib prevents both the activation of the B-cell antigen receptor (BCR) signaling pathway and BTK-mediated activation of downstream survival pathways, inhibiting the growth of malignant B-cells that overexpress BTK[2].
Research Area：Cancer
Targets：Btk
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Kinase Inhibitor Library; Protein Tyrosine Kinase Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Drug Repurposing Compound Library;NMPA-Approved Drug Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Blood Cancer Compound Library;Rare Diseases Drug Library;FDA-Approved Anticancer Drug Library;
Related Small Molecules:JAK3/BTK-IN-1;Elsubrutinib;ARQ 531;PF-06250112;PCI 29732;CHMFL-EGFR-202;Avitinib;RN486;GDC-0834 Racemate;Spebrutinib besylate;Vecabrutinib;BMX-IN-1;Tolebrutinib;BTK-IN-16;(R)-Zanubrutinib;Pirtobrutinib;CTA056;EGFR-IN-40;QL-X-138;ACP-5862;BTK-IN-12;JAK3/BTK-IN-4;JAK3/BTK-IN-6;BTK inhibitor 20;SJF620
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