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NSC 228155
CAS No. : 113104-25-9
Biological Activity：NSC 228155 is an activator of EGFR, binds to the extracellular region of EGFR and enhance tyrosine phosphorylation of EGFR. NSC 228155 is also a potent inhibitor of KIX-KID interaction, inhibits kinase-inducible domain (KID) from CREB and KID-interacting domain (KIX) from CBP, with an IC50 of 0.36 μM[2].
Research Area：Cancer
Targets：EGFR|Epigenetic Reader Domain|Histone Acetyltransferase
Related Screening Libraries:Bioactive Compound Library Plus;Epigenetics Compound Library;Immunology/Inflammation Compound Library;JAK/STAT Compound Library;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Histone Modification Research Compound Library;Anti-Cancer Compound Library;Reprogramming Compound Library;Anti-Hepatitis C Virus Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Transcription Factor-Targeted Library;Protein-protein Interaction Inhibitor Library;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;
Related Small Molecules:RVX-297;NSC81111;BRD4 Inhibitor-19;pp60 (v-SRC) Autophosphorylation Site, Phosphorylated;BMS-690514;UNC6349 (Ket2);Curcumin;GSK6853;Osimertinib-13C,d3;GSK4028;CBP/p300-IN-19 hydrochloride;EGFR-IN-5;FGFR2-IN-3;NSC 694621;SR-0813;Inobrodib;PCAF-IN-2;Genistein;Epertinib hydrochloride;Apabetalone;OF-1;I-CBP112;A-485;UNC-CA359;PLX51107;FKBP12 PROTAC dTAG-7;Osimertinib mesylate;AV-412 free base
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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