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Nitidine chloride
CAS No. : 13063-04-2
Biological Activity：Nitidine chloride, a potential anti-malarial lead compound derived from Zanthoxylum nitidum (Roxb) DC, exerts potent anticancer activity through diverse pathways, including inducing apoptosis, inhibiting STAT3 signaling cascade, DNA topoisomerase 1 and 2A, ERK and c-Src/FAK associated signaling pathway. Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kB pathway[2][3][4][5][6].
Research Area：Cancer|Inflammation/Immunology
Targets：Parasite|Topoisomerase|NF-κB|p38 MAPK|STAT|FAK|Apoptosis|ERK
Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;Apoptosis Compound Library;Cell Cycle/DNA Damage Compound Library;Immunology/Inflammation Compound Library;JAK/STAT Compound Library;Kinase Inhibitor Library;MAPK Compound Library;NF-κB Signaling Compound Library;Protein Tyrosine Kinase Compound Library;Stem Cell Signaling Compound Library;Natural Product Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Antioxidant Compound Library;Differentiation Inducing Compound Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Medicine Food Homology Compound Library;Pyroptosis Compound Library;Cytoskeleton Compound Library;Glutamine Metabolism Compound Library;Traditional Chinese Medicine Active Compound Library;Alkaloids Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Antiparasitic Compound library;Anti-Cancer Metabolism Compound Library;Neurodegenerative Disease-related Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Transcription Factor-Targeted Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Anti-Cancer Natural Product Library;Antidepressant Compound Library;Anti-inflammatory Traditional Chinese Medicine Active Compound Library;Plant-Sourced Natural Product Library;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;
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