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Navtemadlin-d7
Biological Activity：Navtemadlin-d7 (AMG 232-d7) is the deuterium labeled Navtemadlin. Navtemadlin (AMG 232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction, with an IC50 of 0.6 nM. Navtemadlin binds to MDM2 with a Kd of 0.045 nM[2].
Research Area：Cancer
Targets：MDM-2/p53|E1/E2/E3 Enzyme
Related Small Molecules:UBE2T/FANCL-IN-1;MDM2-p53-IN-15;MC-VC-PABC-SP 141;p53 and MDM2 proteins-interaction-inhibitor (racemic);Navtemadlin;MD-224;DI-1859;Mutant p53 modulator-1;MDM2/4-p53-IN-2;MX69;p-nitro-Pifithrin-α;RG7112;MMRi62;Anticancer agent 50;NSC59984;Pifithrin-β hydrobromide;Ivaltinostat formic;GEM-5;Teslexivir;TRAF6 peptide;Tenovin-6;PK11007;AM-8735;NAcM-OPT;GN25;RO-5963;PhiKan 083;C16-Ceramide;Pifithrin-α hydrobromide
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